Volume 6, Issue 1 (12-2020)                   hrjbaq 2020, 6(1): 42-54 | Back to browse issues page

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Ghorbanian B, Saberi Y, Babalooyan S. The Effect of Eight Weeks of High Intensity Interval Training on Plasma Glucagon, GLP-1 and Lipid Indicators in Non-Alcoholic Fatty Liver Patients. hrjbaq. 2020; 6 (1) :42-54
URL: http://hrjbaq.ir/article-1-475-en.html
Department of Exercise Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran , (b.gorbanian@gmail.com)
Abstract:   (232 Views)

Introduction: Non-alcoholic fatty liver disease is a chronic disease that is associated with the accumulation of fats in the liver. Regular exercise can be considered as an effective strategy in the treatment of non-alcoholic fatty liver disease. The aim of this study was to evaluate the effect of eight weeks of intense interval training on plasma levels of glucagon, GLP-1 and blood lipid indices in patients with non-alcoholic fatty liver.
Materials and Methods: The present study was a quasi-experimental study in which the study population was women with non-alcoholic fatty liver disease, 25 of whom were randomly divided into two groups of exercise (n = 13) and control (n = 12). Were. Intense intermittent training protocol was performed for 8 weeks and four sessions per week, each session lasting 60 minutes. Blood samples were taken from the brachial vein in pre-test and post-test conditions. Statistical analysis of data was performed using analysis of covariance and paired and independent t-test by spss21 software at a significant level of p <0.05.
Results: After eight weeks of intense interval training, the glucagon, GLP-1 and HDL plasma levels in the training group increased significantly compared to the control group (P<0.05). Also, LDL, TG, TC, insulin resistance index and body fat percentage in the exercise group had a significant decrease compared to the control group (P<0.05).
Conclusion: According to the findings of this study, intense interval training can be suggested as a treatment and prevention strategy for non-alcoholic fatty liver disease.

Author Contribution: All authors contributed equally in this work.
Conflict of interest/ Funding/ Supports: The authors declare that have no conflict of interest / Funding/ supports in this study.
Ethical Contribution: All ethical concerns respected in this study. It was approved ethical committee of Tabriz University of Medical Sciences (code number: IR.TABRIZ.RC.1399.472).
Applicable Remarks: Use of intense interval training as a non-pharmacological treatment strategy for prevention and improvement of non-alcoholic fatty liver disease.

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Type of Study: Research | Subject: Special
Received: 2020/10/13 | Revised: 2021/02/20 | Accepted: 2020/12/22 | ePublished ahead of print: 2021/01/18 | Published: 2021/02/20

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