Health Research Journal

Introduction: Skin manifestations play a very important role in the diagnosis of various infectious diseases.
Case Report: A 67-year-old woman with fever (39.2° C), fatigue, muscle weakness, and shortness of breath referred to the Medical Emergency Department of Tehran Hospital. From three days before his hospitalization, he had oral ulcers on the back of the tongue and buccal mucosal ulcers, erythematous macules, as well as papules on the palms of the hands, feet, and legs.
Results: Pulse rate, respiration rate, blood pressure and oxygen saturation were 122 beats per minute, 18 beats per minute, 119.78 mm Hg and 91%, respectively. Covid-19-positive or real-time polymerase chain reaction was confirmed with his pharyngeal swab. Chest CT scan showed segmental pneumonia in both lungs with moderate involvement. Laboratory tests significant levels of di-dimer (3.5 μg/L), lactate dehydrogenase (469 mg/L), C-reactive protein (121 mg/L), lymphocyte count (87%) and troponin (065.0 ng/ml). Prothrombin time (17 seconds), partial thromboplastin time (45 seconds), and levels of alanine aminotransferase (69 units per liter), alkaline phosphatase (426 units per liter), ferritin (475 ng / ml) and creatinine (1.85 ml) G per deciliter) was assessed. Loratadine and nystatin were administered for 5 days to treat local pruritus and mucosal lesions, respectively. Finally, after recovery on the sixth day of hospitalization, she was successfully discharged from the hospital under stable conditions with 96% oxygen saturation.
Conclusion: This study showed that erythema multiform can be a new skin manifestation caused by the Covid-19 infection.

Author Contribution: All authors contributed equally in this work
Conflict of Interest/Funding/Supports: The authors declare that have no conflict of interest and/or funding supports in this study.
Ethical Considerations: All ethical concerns respected in this study. Also, it was approved in ethical committee of Baqiyatallah University of Medical Sciences (IR.BMSU.REC.1399.180).  
Applicable Remarks: To help for understanding newer skin manifestations of Covid-19 infection.